Difference Between HGH and Steroids (With Table)

In the human body, there are a lot of systems such as the Endocrine System, Digestive System, Respiratory System etc., which work together so that our body can function properly. The endocrine system is called the messenger system of the human body because it carries message and feedbacks from the hormones released via the gland in our body. Hypothalamus controls all the endocrine systems. Endocrines systems consist of both glands and hormones. Two types of Hormones that are necessary for the growth of the body is HGH and steroids.

HGH vs Steriods

The difference between HGH and Steriods is that HGH is a growth hormone that consists of protein and is secreted naturally by the pituitary gland, whereas Steriods are the compounds that are produced chemically to enhance muscle power appearance and performance. HGH doesn’t have any side effects, whereas steroids have many undesirable side effects. Steriods need to be injected into your body, and it takes time to absorb while HGH is natural, so it gets absorbed easily.

HGH full form is Human Growth Hormone is also known by the name Somatotrophin. It is a peptide hormone which means that it consists of proteins and peptides. The function of HGH is that it helps in the growth, reproduction of cells and regeneration in humans as well as animals. Overall it is important for human development. HGH stimulates IGF-1, i.e. Insulin-like Growth Hormone and also increases the stimulation of fatty acids and glucose. It is also used as a prescription drug for treating children and adults with their growth-related disorders and deficiency.

Steroids are also known as Anabolic steroids. Steriods consists of androgens, i.e. natural or synthetic steroids hormone and are very much similar to testosterone as well as synthetic androgens, which gives the same effects as testosterone. The function of Anabolic steroids is that they increase the proteins inside the cells, especially in the skeletal muscles of the body. Steroids also result in the growth of facial and body hair. If an excessive dose of steroids is taken for a longer period, then humans can have severe health-related problems.

Comparison Table Between HGH and Steriods

Parameters of ComparisonHGHSteriods
Full-Form HGH is known by the name Human Growth Hormone or Somatotrophin.Steroids are known by the name anabolic–androgenic steroids (AAS) or simply Anabolic steroids.
EffectsIt is not addictive and can be easily absorbed into the body.It is addictive in nature and can pose health threats.
UsesIt is used for the treatment of children’s growth disorders and adult growth hormone deficiency.It is used for medicinal purposes such as bone marrow, AIDS and Cancer.
StructureIt consists of 4 helices and 191 amino acids.It consists of 17 carbon atoms bonded with 4 rings.
FunctionsIt helps in the growth, reproduction of cells and regeneration. It increases the proteins inside the cells, especially in the skeletal muscles.

What is HGH?

Somatotropin, as the name suggests, means the growth hormone of human. Firstly growth hormone was discovered in animals and was naturally extracted from carcasses. Then in humans, it is extracted from human cadavers. The structure of HGH is an isoform that consists of 191 amino acids proteins. It has a molecular weight of 22,124 daltons. HGH also contains four helices which are very important for the G.H. receptor. 

Through various research, the similarity between humans and Old World Monkeys growth hormones have been found, which has similar effects.HGH is secreted naturally via the pituitary gland, which in turns get regulated by the hypothalamus. Several factors are responsible for the secretion of growth hormones, such as sex, age, exercise, stress, diet, and other hormones. Like young adolescents secrete HGH at the rate of 700 μg/day approximately, while healthy adults secrete G.H. at the rate of about 400 μg/d.

If there is a deprivation in sleep, then it suppresses HGH, and it can be seen in early adulthood. Increasing the height of children is one of the effects of HGH. It also performs other functions besides increasing heights such as Increases calcium retention, strengthens and increases the mineralization of bone, Promotes lipolysis, Reduces liver uptake of glucose, Stimulates the immune system, Increases protein synthesis, Stimulates the growth of all internal organs, excluding the brain and much more.

What are Steroids? 

Steriods is known by different names such as Anabolic, Androgen etc. Steroids are very much similar to testosterone and even have the same effects. It is not always necessary that steroids are used by only athletes or sportsman. The sales of steroids jumped up to 25% in the year 1999 and 2000 because of the fact for enhancing looks and was being widely used in the cosmetic industry.

There are four common ways through which steroids can be taken into the body: Oral Pills, creams or gel, injections, and skin patches. Oral Pills are the most common way. Steroids are very harmful and become addictive if taken for longer durations. It is not easily absorbed in the body because it is a chemical compound. It has many side effects such as oily skin, acne, stretch marks, reproductive changes, infertility, depression, anxiety, suicidality, psychosis, cognitive impairment, breast atrophy etc.

Steroids are organic compounds that contain four rings and 17 carbon atoms. It has two biological functions, which include components of the cell membrane and as a signalling molecule. The discovery of steroids dates back to 100 B.C.E. in China, and then medically, it was extracted in the late 19th century. Intake and rules regarding steroids vary from country to country. In someplace, it is not illegal but controlled. From all types of major sports, it is banned. 

Main Differences Between HGH and Steriods

  1. HGH is known by the name Human Growth Hormone or Somatotrophin. Steroids are known by the name anabolic–androgenic steroids (A.A.S.) or simply Anabolic steroids.
  2. HGH is not addictive and can be easily absorbed into the body as it is naturally produced. Steriods is addictive and can pose health threats, and it is a chemical compound.
  3. HGH is used for the treatment of children’s growth disorders and adult growth hormone deficiency. Steriods is used for medicinal purposes such as for the treatment of bone marrow, AIDS, Cancer etc.
  4. HGH consists of 4 helices and 191 amino acids proteins. Steriods consists of 17 carbon atoms bonded with 4 rings.
  5. HGH helps in the growth, reproduction of cells and regeneration. Steriods increases the proteins inside the cells, especially in the skeletal muscles.

Conclusion

Both HGH and Steriods are often confused as similar terms. Both have similarities because they are growth-stimulating hormones. But HGH is produced naturally, whereas steroids are synthetic and are taken artificially into the body. Steroids help to retain the protein in the body and is necessary for muscle growth. But it is highly tempting and has severe side effects which can be dangerous to health.

References

  1. https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-2007-1024877
  2. https://kilbydcwms.pbworks.com/w/file/fetch/48366365/Steroids%20in%20America.docx
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