Ibuprofen and aspirin are drugs that are purchased from pharmacies without a prescription from a doctor.
Their most common preventive use is against pain from inflammation, cramps, etc, and is therefore also called pain relief medicines.
They are commonly referred to as over-the-counter medications due to their unprescribed nature.
Key Takeaways
- Ibuprofen is better for reducing inflammation and pain, while aspirin is better for preventing heart attacks and strokes.
- Ibuprofen can cause stomach irritation and bleeding, while aspirin can cause stomach irritation, bleeding, and blood-thinning effects.
- Ibuprofen is available over the counter, while aspirin is available over the counter or by prescription.
Ibuprofen vs Aspirin
Ibuprofen is a medicine with propionic acid as the active ingredient and it is meant for regular use for cramps and headaches, although larger doses will require a prescription from the doctor. Aspirin is a common over-the-counter medicine made with salicylic acid as the main ingredient.
Ibuprofen has a definite dose that is meant for regular uses such as headaches or cramps. In case a patient wants higher doses to counter their pain, then they need a prescription from the doctor, without which the pharmacist might refuse to provide the high-dose medication. This is because such higher doses might give rise to side effects that might be chronic.
Aspirin is a common household medicine name that almost all houses have in their first-aid box. One of the most common over-the-counter medicine in India is aspirin. Their doses are always kept in check by the pharmacists to make sure that the purchasers don’t overdose and get a major side effect if used for a long.
Comparison Table
| Parameters of Comparison | Ibuprofen | Aspirin |
|---|---|---|
| Active Ingredient | Propionic acid | Salicylic acid |
| Regular Dose | 200 mg | 325 mg |
| Can be Taken By People With Cardiovascular Issues | No | It’s not an issue |
| Is a Risk to People With Clotting Issues | No | Yes |
| Better for Long Term | Yes | No, unless for heart issues |
What is Ibuprofen?
Ibuprofen is a common painkiller used by people all over to get relief from recurring pain.
The active ingredient in ibuprofen is propionic acid. It is a three-carbon compound, with the third carbon being a part of the acid side chain.
The two-carbon chain that the acidic group is attached to is the reason ibuprofen is different from its sister pain relief medicines.
Ibuprofen isn’t always sold under the chemical name, but rather it has a few brand names that might change with the country of origin or country of sale.
In India, it’s more commonly known to the common mass as Advil or Motrin.
The major action of ibuprofen is to inhibit an enzyme that causes inflammation.
Inflammations can be a reason for massive pain in the sites of action.
Ibuprofen inhibits the enzyme cyclooxygenase, which is more commonly called COX enzyme among the medical fraternity.
COX prevents the activated formation of prostaglandins, which are the major reason for the formation of inflammation.
The regular dose of ibuprofen that pharmacists provide for pain relief is 200 milligrams.
It can be taken within an hour gap of 4-6 hours, depending on the intensity of the patient is pain.
It is advised to not keep having the medication in a small-time gap, such as an hour or so.
But that doesn’t mean it isn’t prescribed in smaller doses for long-term use by doctors for those who might need its effects to cure something bigger.
A few side effects of ibuprofen include nausea and diarrhea, along with headaches and abdominal pains.
People who have a history of cardiovascular issues are always advised not to have ibuprofen medicines as they might aggravate their problems.
High doses of ibuprofen can lead to kidney failure and peptic ulcers.
What is Aspirin?
Aspirin is the most commonly gone for pain relief medicine.
The main ingredient in aspirin is salicylic acid which gives it a unique difference from other painkillers out on the market.
It has seven carbon atoms, including the carbon from the -COOH of the acidic group.
It has many brand names other than the chemical name of aspirin.
In India, it is commonly present in pharmacies under the name of Bayer or Ecotrin.
Their major site of action is the glands that produce prostaglandins that cause inflammation.
Aspirin, therefore, inhibits the formation of the enzyme cyclooxygenase, which helps in the formation of prostaglandins.
A regular dose of aspirin is 325 milligrams.
Each dose can be taken with a time gap of over 5 hours to enhance the activity of the medication.
Higher doses are strictly kept a tab off by medical practitioners and even the local pharmacists.
The higher the dose, the greater would be the side effects and the longer it would affect the individual.
Long terms are not recommended as they might lead to kidney failure issues.
But if a doctor prescribes long-term aspirin usage, it might be in cases of patients with a history of heart attacks or strokes.
But the doctors have always prescribed a low dose of about 81 milligrams for such long-term courses.
This low dose is commonly called baby aspirin.
Baby aspirin is a daily taken medicine for people with chronic heart disorders.
Those people with a greater risk of bleeding are advised not to have aspirin as it might aggravate the situation.
Even people with kidney failures are advised to keep away from aspirin.
Main Differences Between Ibuprofen and Aspirin
- While the active ingredient in ibuprofen is propionic acid, that in aspirin is salicylic acid, both of which have a difference in their carbon numbers.
- The common brand names of ibuprofen are Advil and Motrin, while aspirin is Bayer and Ecotrin.
- It is more common for ibuprofen to be used as a long-term medication than aspirin because the amount of side effects shown by ibuprofen tends to be less in the long run.
- The regular dose limit of ibuprofen is 200mg, the bare minimum required to help them overpower their pain, while that of aspirin is 325mg.
- Ibuprofen shows side effects for those with cardiovascular disorders, while aspirin is known to cure it.
- https://www.acpjournals.org/doi/abs/10.7326/0003-4819-91-6-877
- https://www.ahajournals.org/doi/abs/10.1161/01.cir.101.10.1206
Last Updated : 13 July, 2023
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Sandeep Bhandari holds a Bachelor of Engineering in Computers from Thapar University (2006). He has 20 years of experience in the technology field. He has a keen interest in various technical fields, including database systems, computer networks, and programming. You can read more about him on his bio page.
The author did a great job of presenting the information about Ibuprofen and Aspirin in a clear and understandable manner. The differences between these drugs are significant, and people should be aware of the potential risks associated with their use. Responsible use of over-the-counter medications is essential for public health and safety.
I appreciate the effort to present a detailed comparison of these pain relief medications. However, it is evident that the risks associated with their use are significant and should not be underestimated. It is essential for people to be aware of these risks and use these drugs responsibly, following the advice of healthcare professionals.
I found the article very informative. Despite the fact that people often use Ibuprofen and aspirin interchangeably in order to relieve some symptoms, especially pain; both drugs have differences and potential risks that should be taken into account. It is important to be cautious with these types of drugs and to use them responsibly.
I totally agree with you, Freya. People should be aware of these differences in order to make the best decision about which drug to use. A responsible use of medicine is crucial in order to avoid complications.
You’re right, Freya. I particularly liked how the author presented the main differences between Ibuprofen and Aspirin. I think it is essential for people to understand that these are different drugs, and even though they serve the purpose of relieving pain, the risks they can pose are quite different.
The article provides valuable information about Ibuprofen and Aspirin, shedding light on their differences and potential risks. It is crucial for people to be aware of the risks associated with these drugs and use them responsibly. I believe that raising awareness about the differences and potential risks of these medications is of great importance for public health.
The article is well written and provides an excellent comparison between Ibuprofen and Aspirin. It is important for readers to understand the differences between these drugs in order to make informed decisions about their use. The potential risks associated with each medication should be taken into consideration for a responsible and safe use of pain relief medicines.
I completely agree, Kieran. It is crucial for people to have access to this type of information, which can help them avoid unnecessary risks when using over-the-counter medications. The risks associated with Ibuprofen and Aspirin are significant and should not be overlooked.
It is clear that the author made a great effort to provide detailed information about this topic. However, I believe that there is a great risk of people misusing this information to buy the drug that gives them the most immediate effects, without considering the potential risks they might be taking. This is a critical issue that should be urgently addressed.