Difference Between INR and APTT

Blood tests are one of the important health observation tests. Blood tests have many types. Different factors are tested according to the symptoms of the patients. One of those symptoms is heavy bleeding. If a person has this cause, they are prescribed to undergo INR and APTT tests. Both of these are used to measure blood clot time but have some specialties. So here are some differences between them to understand these tests better.

INR vs APTT

The main difference between the INR and the APTT test is that in the INR test, the heparin level is not measured, but it is measured in the APTT test. On the other hand, in the APTT test, the Prothrombin and fibrinogen are not measured, which is examined in the INR test. 

INR and APTT

The full form of INR is International Normalized Ratio. It is a blood test. This test is also called PT. The full form of PT is Prothrombin Test. This test is done to measure the blood clotting time. The consistency of blood is also determined by this test. Sometimes patients who have some disease or are gone under any operations have thin blood. 

APTT test is used to detect Heparin therapy as well as blood clotting range. Heparin is a anticoagulant. This helps to stop the blood clot. If the level of heparin is too high, it may lead to thinning of blood and lower blood clotting. Lower blood clotting is a dangerous problem as it can lead to heavy blood loss.

Comparison Table Between INR and APTT

Parameters of ComparisonINRAPTT
Full formInternational Normalized Ratio is the full form of INR. Activated Partial Thromboplastin Time is the full form for APTT.
Used to detectThis is used to detect Blood clotting time.This is used to detect Heparin therapy as well as blood clotting range.
Clotting factorsThis can assess the coagulation factors XII, XI, IX, VIII, X, V, II, I.This can assess the coagulation factors V, VIII, IX, X, XI, XII.
Heparin sensitivityLess sensitiveMore sensitive
Normal range10 to 14 seconds30 to 40 seconds

What is INR?

The full form of INR is International Normalized Ratio. It is a blood test. This test is also called PT. The full form of PT is Prothrombin Test. This test is done to measure the blood clotting time. The consistency of blood is also determined by this test. Sometimes patients who have some disease or are gone under any operations have thin blood. Thin blood problems also occur if they are taking certain kinds of medicines called an anticoagulant.

 The coagulation of blood is very necessary for organisms. There is a component of blood called platelets. They gather together at the affected area and stop the blood flow. If the clotting time is too fast or slow is not good. The number of platelets is always counted if the patient undergoes heavy bleeding conditions.

The coagulation factor II is called Prothrombin, and the I is known as fibrinogen. Prothrombin is a protein produced by the liver. Like many other proteins, this is also an important protein that contributes to blood clotting.

This test is a part of the blood test prescribed by the doctor. Some other tests are also done to check the heparin level of the patient as the INR test is less sensitive to Heparin.

What is APTT?

Activated Partial Thromboplastin Time is the full form for APTT. This test is also done to calculate the coagulation time. This is done under a blood test. Here all the coagulation factors are examined except the Prothrombin and fibrinogen. These two are measured by the INR test.

APTT test is used to detect Heparin therapy as well as blood clotting range. Heparin is a anticoagulant. This helps to stop the blood clot. If the level of heparin is too high, it may lead to thinning of blood and lower blood clotting. Lower blood clotting is a dangerous problem as it can lead to heavy blood loss. The normal range of APTT is 30 t0 40 seconds for a healthy adult.

This test can assess the coagulation factors V, VIII, IX, X, XI, and XII. This test is more sensitive to heparin, so it is always prescribed by doctors. This test is prescribed if a person is having huge blood losses like heavy menstruation or nose bleedings, liver disease, any operation, or accidental blood loss. This test explains that how healthy the body is as the blood clotting process is a very important part of a healthy person. The platelets are also counted in this test.

Main Differences Between INR and APTT

  1. International Normalized Ratio is the full form of INR. On the other hand, Activated Partial Thromboplastin Time is the full form for APTT.
  2. INR test is used to detect Blood clotting time, but in comparison to that, the APTT test is used to detect Heparin therapy as well as blood clotting range.
  3. INR test can assess the coagulation factors XII, XI, IX, VIII, X, V, II, I in contrast to that APTT test can assess the coagulation factors V, VIII, IX, X, XI, XII.
  4. INR test is less sensitive to heparin, but in comparison to that, the APTT test is more sensitive to heparin.
  5. The normal range of the INR test is 10 to 14 seconds on the other hand, the normal range of the APTT test is 30 to 40 seconds.

Conclusion 

Health is a very important asset of a person. This is even more important than money. So health should always be the priority of everyone. When a person crosses a certain age, they should always be under heath observations for a healthy life. 

The differences between the INR and APTT tests are discussed. Both are parts of the blood tests regarding the blood clotting factor. They are equally important are of highly concerning factors. The normal levels of these should be maintained to lead a healthy life. 

References 

  1. https://www.sciencedirect.com/science/article/pii/S004938480600243X
  2. https://www.sciencedirect.com/science/article/pii/0049384894902720
  3. https://www.researchgate.net/profile/Husamettin-Vatansev/publication/280443384_Effect_of_gender_and_age_on_the_prothrombin_time_PT_activated_partial_thromboplastin_time_aPTT_levels_and_international_normalized_ratio_INR/links/55dc5e5b08aeb38e8a8cf07e/Effect-of-gender-and-age-on-the-prothrombin-time-PT-activated-partial-thromboplastin-time-aPTT-levels-and-international-normalized-ratio-INR.pdf
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