Difference Between Blood and Plasma

Blood and plasma are two liquids of prime importance for the body. While blood is primarily responsible for transporting nutrients, plasma is a component of blood. A lot of individuals often confuse plasma as a different fluid, but in reality, it is a component that makes up blood.

Blood vs Plasma

The main difference between blood and plasma is that blood is used for circulating nutrients and oxygen throughout the body. On the other hand, plasma is one of the many components of blood. It does not play a direct role in various metabolic processes that occur in the human body.

Blood vs Plasma

Blood is the red fluid that oozes out of the body when a person gets injured. It is the liquid component of the human body and is made up of different types of cells. It plays a very important role in the circulation and transportation of nutrients to all the cells of the body equally.

Plasma can be referred to as the major component of blood. It forms up to 50% of the consistency of blood. It is made up of a combination of different salts and proteins. It is white to yellowish and is responsible for increasing the volume of blood in the body.

Comparison Table Between Blood and Plasma

Parameters of ComparisonBloodPlasma
Color and consistencyBlood is red and the shade mainly depends on the ratio between different components. Plasma is yellow because it does not contain any color giving pigments.
The main function The main function of the blood is associated with the transportation of Micro and micronutrients across different cells. The main function of plasma is associated with volumizing the blood. This way, the transportation of the fluid becomes easy.
ConstituentsBlood is made up of plasma, red blood cells, white blood cells, and platelets. Plasma is made up of different salts and proteins. There is no cellular component in plasma as opposed to blood.
CompatibilityBlood transfusion requires a lot of tests to determine whether it will be compatible person’s body or not. There are no incompatibility issues associated with plasma. This is the reason why it is preferred over blood for injuries.
ClottingBlood clots with the help of platelets and can be seen as over minor and major injuries. Plasma is transformed into serum after clotting. The serum is very beneficial in medical treatments and requires utmost care.

What is Blood?

What happens when you get a minor or major cut on any part of your body? You see that a red-colored fluid oozes out from that spot. The red-colored fluid is known as blood and performs the circulation processes in the body.

Blood has different cellular components in it. The red blood cells are responsible for carrying oxygen to different cells of the body. They are red due to a pigment called hemoglobin. If a person has less hemoglobin in their blood, the cells are not able to get enough oxygen for good functioning.

The white blood cells are referred to as the saviors of the body. They help in preventing infections and fight disease-causing microorganisms. Even though they are called white blood cells, they can be colorless. They have an irregular shape and can be found in different forms.

The blood also has platelets that are responsible for the process of clotting. Clotting is very important to prevent excessive loss of blood after injuries. The clotting time of different blood groups can be varying. However, it must not exceed a few seconds as it may result in the excess loss of blood.

What is Plasma?

Plasma is a major part of blood and provides it a fluid form. This is because the other components are cellular and naturally solid. The liquid nature of the blood is a result of a major fraction of plasma in it.

Plasma is made up of proteins and salts. It is yellow and has more fluidity than blood. It accounts for more than 50% of the constitution of blood. It is used for treating a variety of diseases. This is because it contains antibodies that are responsible for killing harmful pathogens in the body.

Patients who suffer from trauma and liver orders are given plasma therapy. One advantage of plasma is that it does not need compatibility tests. When blood transfusion is done, a compatibility teat is necessary as the receiver’s body made rejects the blood. Therefore, plasma becomes a better option in the case of patients with severe trauma.

Nowadays, a lot of people donate plasma so that they can help people in need. People with common blood groups are always in demand for donating plasma. Plasma helps in transporting hormones to different parts of the body. The hormone level in different cells is important to maintain for good health.

Main Differences Between Blood and Plasma

  1. Blood is red while plasma, on the other hand, is yellow-colored. Additionally, blood is a lot thicker than plasma, which is its constituent.
  2. Blood plays a direct role in the transportation of nutrients across the body. Plasma plays an indirect role in the transportation of hormones in the body.
  3. Blood has cellular components while plasma does not have any cellular components.
  4. Blood can be donated in its original form while plasma needs to be separated from blood call donation.
  5. A compatibility test needs to be done for blood transfusion. Plasma does not need a compatibility test.


Both blood and plasma have a very important role in maintaining the overall health of the body. They have a variety of uses in the treatment of patients who meet with minor and major accidents. The serum obtained from plasma is of utmost importance for medical therapy In today’s time when a large number of diseases are prevailing, plasma can be very helpful. Anemia has become very common, especially in children. Foods that have a high content of iron are needed for people who are anemic. Regular blood tests can be performed to ensure that the body is free from disease-causing microorganisms.


  1. http://www.informatics.jax.org/greenbook/chapters/chapter17.shtml
  2. https://www.annualreviews.org/doi/pdf/10.1146/annurev.bi.19.070150.002205
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