Difference Between Mollicutes and Mycoplasma

Mollicutes and Mycoplasma are both types of bacteria that lack a cell wall.

Mollicutes are parasites that live on or in the cells of other animals and plants. They are the smallest self-replicating and free-living life forms.

Mollicutes reproduce by budding instead of binary fission. These are parasites that colonize their hosts and resist their immune systems.

Many can move by gliding, while some are helical so can only move by twisting. They cause problems in Humans by sticking to respiratory or urogenital tract cells.

Mycoplasma is one of the genera within the class Mollicutes. They lack cell walls and vary in size from spherical to filamentous.

The mycoplasma cell has the bare minimum of organelles required for development and replication: a plasma membrane, ribosomes, and a genome made up of a double-stranded circular DNA molecule.

Mycoplasma is called the “crabgrass” of cell culture due to their diagnosis being difficult to diagnose and treat.

Comparison Table Between Mollicutes and Mycoplasma

Parameter of ComparisonMollicutesMycoplasma
DefinitionMollicutes are the least complex and smallest self-replicating and free-living single – cell organisms known to science.Mycoplasma is a genus under the Mollicutes class. they are so little in comparison to other bacteria and lack cell walls
TaxonomyA combination of the Latin words “mollis,” which means “soft” and “cutis,” which means “skin.”Derived from the Greek words “mykes,” which means “fungus,” and “plasma,” which means “made
EtymologyClass of bacteriaGenera within the class pf bacteria

What is Mollicutes?

The word Mollicute is derived from the Latin word “Mollis” which means soft and “Cutis” which means skin. Mollicutes are the smallest self-reproducing and free-living forms of life.

They lack a bacterial cell wall. Mollicutes are parasites that live inside the cells of various animals and plants.

They colonize the host and resist their immune system. They can cause many different diseases in humans by attaching to urogenital and respiratory tracts.

Individuals are generally relatively tiny, with a very minimal genome size. They vary in shape, but most include sterols, which harden the cell membrane.

Many organisms can move by gliding, however Spiroplasma members are helical and move by twisting.

Mollicutes have developed through reproductive evolution from gram-positive bacteria. Lacking cell walls, they reproduce by a budding mechanism rather than binary fission.

The three genera of Mollicutes that can cause problems in humans are Erysipelothrix, Ureaplasma, and Mycoplasma.

What is Mycoplasma?

Mycoplasma is derived from the Greek words “mykes” (fungus) and “plasma” (formed). Mycoplasma is a genus under the Mollicutes class.

They are extremely small compared to other bacteria and lack cell walls, therefore some antibiotics do not affect them.

Because they lack cell walls, these microorganisms may change form and are pleomorphic.

Mycoplasma lack nucleus and other organelles. They have a replicating disc at one end that helps in replication and the separation of genetic components.

The parasitic nature is due to mycoplasmal bacteria’s inability to synthesise the essential growth component.

Although not all mycoplasmas cause disease, there are a few which can be dangerous.

Those which can cause disease include Mycoplasma pneumonia, Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma urealyticum, and Ureaplasma parvum.

Main Differences Between Mollicutes and Mycoplasma

  1. Mycoplasma is a genus under the Mollicutes class. Since they are so little in comparison to other bacteria and lack cell walls, some antibiotics do not work against them. There are about 200 different types of mycoplasma bacteria. Mollicutes are the least complex and smallest self-replicating and free-living single-cell organisms known to science. This class of basic bacteria is characterized by the absence of a bacterial cell wall and their small genomes, which contain the whole set of genetic instructions in cells. Mollicutes are polar and have reasonably well-defined forms; they are mainly delineated by a cholesterol-containing unit membrane.
  2. The term “mollicutes” is a combination of the Latin words “Mollis,” which means “soft” or “pliable,” and “cutis,” which means “skin.” Mycoplasma, on the other hand, is derived from the Greek words “mykes,” which means “fungus,” and “plasma,” which means “made.” 
  3. Mollicutes is a class of bacteria; mycoplasma is one of the genera within the class Mollicutes.

Conclusion

Mollicutes are the simplest and smallest self-replicating and free-living life forms that science has discovered.

Mycoplasma is one of the genera within the class Mollicutes.

Mollicutes are polar and have reasonably well-defined forms; they are solely defined by a cholesterol-containing unit membrane.

Many mollicutes were previously misidentified as viruses because of their ability to be filtered by many different types of viruses.

Since Mycoplasma is really tiny compared to other bacteria and lack cell walls, several antibiotics do not work against them.

They are bacteria capable of infecting the lungs, skin, and urinary tract. They are quite tiny compared to other bacteria.

As a result, certain antibiotics are ineffective against them. There are over 200 different forms of mycoplasma bacteria.

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