Difference Between Gamete and Zygote

Development is a complicated process that progresses in the form of a series of essential steps. At each step, a lot of structural and functional changes take place to maintain the required status of the fetus at the right time.

Gametes and zygotes are formed during the initial stages and play an important role in the determination of the final sex of the ovum. The chronology remains the same – zygote after fusion of the two gametes (X or Y).

Gamete vs Zygote

The main difference between gamete and zygote is that gamete is the participatory unit during fertilization while zygote is the by-product of fertilization. The final status of the zygote is determined by the types of gametes that participate in fusion – similar X cells lead to female composition while a combination of XY leads to male composition.

Gamete vs Zygote

A gamete is divided into two sub-categories which include egg (female gamete) and sperm (male gamete). They are partially distinguished from each other.

Unless and until fusion takes place, the gametes cannot express themselves in their actual state and remain non-functional.

A zygote is a spherical mass formed as a result of fusion. It is the first stationary phase and marks the onset of attachment of the resultant mass inside the womb.

Other developmental stages follow suit. In other words, two haploid cells combine to form a diploid cell.

Comparison Table Between Gamete And Zygote

Parameters of ComparisonGameteZygote
DefinitionIt is one of the germ cells (male or female) that is involved in the process before fertilization. It is the fertilized ovum which is the product of fertilization of two cells (haploid).
Final Product ProducedZygote.Fetus.
MovementThe male cell is capable of movement, the female cell is not. No movement is possible.
Cell Composition Single chromosome and single autosome copy. Either pair of chromosomes and double autosome copy.
TypesMale gamete and female gamete. The final zygote is an exclusive type in itself.

What is Gamete?

A gamete is a simple sex cell. It regulates the expression of male or female characters in the fused mass.

Therefore, the resultant sex is determined by the original gametes which participate in the fusion. While some researchers leave it on chance, others have established that the fusion of two X chromosomes is more likely than the fusion of an X chromosome with a Y chromosome.

A gamete is just a mode of the combination post copulation.

This is because X (female) is always fixed. The determination is completely based on which of the sperm (X type or Y type) will fuse the egg. Though the probability is considered to be fifty percent due to the equal composition, it might not apply in all cases.

As far as the location is concerned, the female gamete is located in the female reproductive system (ovaries), and the male gamete is in the male reproductive system (testicles).

A male gamete cannot fuse with a male gamete while a female gamete can. This means that an X chromosome is allowed to fuse with either the X or Y chromosome. On the other hand, a Y chromosome can only unite with the X chromosome and not the Y chromosome.

The former case leads to a resultant female while the latter is the composition of a male.

What is Zygote?

A zygote is a fertilized unit that attaches to the fallopian tube after fusion and goes through a series of developments to ultimately become the fetus. It can also be referred to as the first stage when the fetus gets its original identity.

The etymology is as follows – zygote has been derived from the Greek word “yoked” which means “to join”. In this process, the male gamete is joined with the female gamete, resulting in the subsequent fusion of the two.

The total number of chromosomes that constitute a chromosome is 46 – 23 from the male gamete and 23 from the female gamete respectively. As far as the size is concerned, a zygote is bigger than the gametes which participated in its formation.

The shape turns spherical in some days and ultimately takes the shape of a developed embryo. The movement is restricted due to the process of permanent implantation in the fallopian tube.

It also determines the success rate of the fertilization that took place in the earlier stage. Unless the zygote attaches itself to the fallopian tube, the implantation process cannot progress.

Consecutively, the growth of the embryo is also barred. The resultant fetus may or may not survive due to uncertainty of survival conditions in such a fatal scenario.

Main Differences Between Gamete And Zygote

  1. A gamete is defined as a sex cell (either male or female) which is the beginning unit of fertilization. On the other hand, a zygote is the combined result of fertilization which has a separate identity of its own.
  2. The resultant unit on the fusion of gametes is the zygote itself, while the zygote does not undergo any further fusion but develops into a fetus as time progresses.
  3. As far as motility is concerned, gamete can move in a limited manner (only male) while the zygote is a fixed entity, incapable of any kind of movement.
  4. A gamete is made up of one type of chromosome (either X or Y) and includes an autosome copy. On the contrary, a zygote always consists of a pair (similar or different) and two copies of autosomes are included.
  5. The two exclusive types of gametes are – male (Y chromosome) and female (X chromosome). Since a zygote is diploid in nature, it is not further subcategorized into any other types.
Difference Between Gamete and Zygote


The confusion between the existence of gametes and zygotes occurs due to the large number of stages involved in development. If understood discretely, the two of them are just consecutive stages – the zygote follows the fusion of gametes.

Though there are structural and functional differences at each stage, the morphology remains more or less the same. Further stages are dependent on these two only.

In the context of progression in size, a zygote cannot be formed without gametes. On the other hand, gametes can not further their development without taking the shape of a zygote.

Thus, both the stages are interdependent and have their own significance in the life cycle of an embryo. It is true that the effect of fusion lasts long and the zygote’s composition determines the future health and structure of the former egg.


  1. https://link.springer.com/article/10.1007/BF01134577
  2. https://www.tandfonline.com/doi/abs/10.1080/00071619200650241
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