Difference Between IVF and IVM

There are hundreds of reproductive technology available nowadays. The IVF(In vitro fertilization) and IVM( In Vitro maturation) are two different reproductive technology. Both of them are famous reproductive technology. Both IVF and IVM are helpful for millions of people.


The main difference between IVF and IVM is their performance. The IVF is nothing but doing in vitro fertilization. The IVM is nothing but doing in vitro maturation. In-vitro fertilization has five stages, whereas In vitro maturation has seven different phases. The IVF began from the fertilization of an egg, whereas IVM started from the maturation of the egg.


IVF stands for In Vitro Fertilization. Fertilization of female egg and male sperm is called IVF. All the processes are in the Vitro culture or laboratory. It is called the ovulatory process. In IVF the eggs are removed from the ovaries and fertilized outside the human body. It is all done in In Vitro Culture. This process is called In Vitro Fertilization(IVF).
The fertilized egg is called a zygote which undergoes embryo development for two to six days. After the embryo culture, the zygote is implanted in the mother’s uterus for pregnancy.

In Vitro Maturation is the contrast process of In Vitro Fertilization. In IVM the eggs are getting mature outside the human body. Women who can not undergo ovarian stimulation may have a chance to get pregnant by In Vitro Maturation. It is complicated when compared to In Vitro Fertilization. In Vitro Maturation has more disadvantages. It is an expensive one and needs more time. The immature oocytes from the women can be removed. It helps for the better maturation of oocytes.

Comparison Table Between IVF and IVM

Parameters of comparisonIVFIVM
Ultrasounds neededIVF need 6-10 ultrasoundsIVF need 4 ultrasounds
Blood testsIVF need 6-10 blood testIVM need 0-2 blood tests
Average success rateThe average success rate of IVF is above 46%The average success rate of IVM is 35-40%
Main ProcessFertilization is the primary processMaturation is the primary process
Stands forIVF stands for In Vitro FertilizationIVM stands for In Vitro Maturation

What is IVF?

Infertility is a big issue among couples who are looking to raise a child. IVF is a solution for infertility and it works by assisted reproductive technology. Sometimes the surrogate is not the original mother of the resulting child. Depending on the health of the women the IVF treatment varies and the cost and availability also varies. The pregnancy term also varies on the IVF treatment. Louise Brown was the first child born by IVF in 1978. In Louise Brown’s case, no stimulation is done instead they follow the natural IVF cycle for better results.

Using this IVF method and egg donation can make pregnancy possible. Around eight million children are born by In Vitro Fertilization. The term “in vitro” is a Latin term that means “in glass”. The process of doing things in culture or laboratory is called In Vitro Fertilization. The babies born by IVF are called test-tube babies. In Vitro fertilization can be found to overcome the female infertility range.

In IVF, no drugs are used for the stimulation of the ovaries. But still, for the suppression process, they use certain drugs. Frozen embryo transfer, ovarian hyperstimulation, embryo cryopreservation, embryo transfer are the primary steps of IVF. Around two months taken for a single cycle of In Vitro Fertilization. The administration process in IVF is quite a discomfort for the women who undergo IVF.

What is IVM?

In Vitro Maturation is not a healthy technique. The In Vitro Maturation culture is rich in gonadotrophin. When compared to IVF, IVM has no birth rates. If a family with estrogen associated thrombus, then IVM causes severe cardiovascular disease. The IVM is a part of IVF. In biology, the IVM is called Oocyte In Vitro Maturation. Diminished egg reserve or polycystic ovarian syndrome (PCOS) are the reasons for not getting pregnant. They may block the mature of the eggs.

The IVM involves eight different steps. Initially, the blood test is done to detect any blood-related problems are available. During the third day of periods, an ultrasound is performed. After confirming the presence of eggs, human chronic gonadotropin is injected. The HCG will induce the ovulation process. After 36 hours, the immature eggs present in the womb are removed. The immature eggs are placed in the culture to get matured. The culture contains Cumulin and c-AMP

In IVM culture the immature eggs are getting matured. The matured egg undergoes the fertilization process. In fertilization, intracytoplasmic sperm injection is done. It left for five to six days to develop. The embryo is transferred to women after administering enough hormones. It is implanted into the uterus. It takes one to two weeks to confirm the pregnancy.

Main Differences Between IVF and IVM

  1. In IVF, the fertilization of women’s eggs with men’s sperm is done. In IVM, maturation of eggs is done.
  2. IVF is a large procedure, whereas IVM is a small procedure.
  3. IVF stands for In Vitro Fertilization, whereas IVM stands for In Vitro Maturation.
  4. When compared to IVF, IVM needs less more medical care and medications.
  5. The average success rate of IVF is above 46%, whereas the average success rate of IVM is 35-40%.


Both IVF and IVM are two different types of reproductive technology. In Vitro Fertilization is nothing but fertilizing the female egg and male sperm outside the human body. the In Vitro Maturation is nothing but mature the immature oocytes in the laboratory. Both the process needs care and patience. Both of them have risk factors and do not have a 100% success rate. It is vital to consider your health before undergoing any inseminations. Fertilization is the primary process of IVF, whereas maturation is the primary process of IVM. Both IVF and IVM are helpful to millions of people to get their babies.


  1. https://www.sciencedirect.com/science/article/pii/S1472648310606992
  2. https://www.sciencedirect.com/science/article/pii/0378432096015308
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