Difference Between Tdap and DTaP

Vaccines are a safe and extremely efficient method of disease prevention. Tdap and DTaP are two widely used vaccinations. They are combination vaccinations, which means they include many immunizations in a single dose. 

They are mainly used for immunity against diphtheria, tetanus, and whooping cough.

Their main differences lie in the number of doses that are required to be administered and the recommended age of administration.

Tdap vs DTaP 

The main difference between Tdap and DTaP is that Tdap stands for Tetanus diphtheria (acellular) pertussis which is administered through 1 single dose to people of age 11 and up and DTaP stands for Diphtheria Tetanus (acellular) Pertussis which is administered through 4 to 5 doses to kids aging 6 weeks to 6 years old. 

Tdap vs DTaP

Tdap is a booster vaccination given to adolescents beginning at the age of ten and adults to offer continuing protection against diphtheria, tetanus, and whooping cough. It is marketed under the brand names Adacel and Boostrix. 

Tdap vaccination might cause pain, redness, or swelling where the injection was given, mild fever, headache, weariness, and nausea, as well as vomiting, diarrhea, or stomachache. 

DTaP is a vaccination that helps provide immunity against 3 diseases and is administered through 4 to 5 doses as per the doctor’s instructions. It is marketed under the brand names Daptacel and Infanrix.

It can be administered to kids within the age of 6 weeks and 6 years.   

Comparison Table Between Tdap and DTaP 

Parameters of Comparison Tdap DTaP 
Vaccine Name Tetanus diphtheria (acellular) pertussis Diphtheria Tetanus (acellular) Pertussis 
Age 11 years of age and above. 6 weeks through 6 years. 
Doses needed 1 dose 4 to 5 doses. 
Brand Adacel, Boostrix Daptacel, Infanrix 
Purpose Boosts immunity against 3 diseases. Provides immunity against the 3 diseases. 
Side Effects Pain, redness, swelling, headache, tiredness, etc. Fever, swelling, soreness, loss of appetite, etc. 

What is Tdap? 

There is a booster vaccination that just comprises tetanus and diphatheria (called Td), but because protection against pertussis fades more slowly, the vaccine Tdap was created.

In 2005, older children and adults were able to receive Tdap immunization. Your doctor will choose whether a booster (Td or Tdap) is best for you. 

Tdap contains inactivated forms of the toxin generated by bacteria that causes these three disorders.

The word “inactivated” alludes to the fact that the toxin no longer causes illness, but it does stimulate the production of antibodies that confer protection against the toxin. 

Despite the fact that it protects against the same diseases as DTaP, the vaccine doses in Tdap are less than those in DTaP since it is only administered as a booster dose.  

Tdap is an acronym for: 

  • Tetanus is abbreviated here as T 
  • Diphtheria is abbreviated here as D. 
  • Pertussis is abbreviated here as P. 

Adacel and Boostrix are two brand names for Tdap. The suggested timing for Tdap booster vaccination is as follows: 

  • around 11 or 12 years 
  • every 10 years after the initial dose

Pregnant women should have a Tdap vaccine between weeks 27 and 36 of their pregnancy. 

What is DTaP? 

The DTaP vaccination protects infants aged 6 weeks to less than 7 years from three potentially lethal bacterial illnesses. The abbreviation DTaP stands for three diseases: 

  • Diphtheria is abbreviated here as D. 
  • Tetanus is abbreviated here as T. 
  • Pertussis is abbreviated here as P. (This is the medical term for whooping cough). 

The toxin produced by the microorganisms that cause these three illnesses is rendered inactive by DTaP.

The word “inactivated” alludes to the fact that the toxin no longer causes illness, but it does stimulate the production of antibodies that confer protection against the toxin. 

DTaP is marketed under the brand names Daptacel and Infanrix. 

DTaP is only available to children under the age of seven. Vaccinations like Tdap are available only for older children, adolescents, and adults. The proposed period for DTaP is as follows: 

  • at 2 months, 4 months, and 6 months 
  • between 15 months and 18 months 
  • between 4 years and 6 years 

Some people have soreness or swelling, fever, fussiness, fatigue, lack of appetite, and vomiting after receiving DTaP immunization.

Seizures, continuous crying for three hours or longer, or a high temperature (above 105°F) following DTaP immunization are far less common.

Vaccination seldom results in extensive swelling of the arm or leg, particularly in older children getting their fourth or fifth dose. 

Main Differences Between Tdap and DTaP 

  1. Tdap stands for Tetanus diphtheria (acellular) pertussis, whereas DTaP stands for Diphtheria Tetanus (acellular) Pertussis. 
  2. Tdap is administered to people who are 11 years of age or older to help boost their immunity. On the other hand, DTaP is administered to children 6 weeks to 6 years of age to help provide them with immunity. 
  3. Tdap is administered in a single dose, and DTaP is administered in 4 to 5 doses. 
  4. Tdap is under the brand names Adacel and Boostrix, whereas DTaP is under the brand names Daptacel and Infanrix. 
  5. Tdap helps in boosting the immunity against 3 diseases are diphtheria, tetanus, and whooping cough, and DTaP helps provide immunity against the 3 diseases these vaccines work against. 
  6. Some of the side effects of Tdap may include pain, redness, or swelling in the area of the vaccination, headache, muscle ache, swollen glands, upset stomach, vomiting, nausea, tiredness, etc. Some of the side effects of DTaP include soreness, swelling, fussiness, vomiting, seizures, fever, loss of appetite, etc. 
Difference Between Tdap and DTaP

Conclusion 

Vaccinations often only provide protection for a limited time, which varies amongst immunizations. Experts suggest that everyone obtain tetanus and diphtheria booster vaccine every ten years.  

DTaP can be given as a separate vaccine or as part of a combination immunization (a type of vaccine that combines more than one vaccine together into one shot). DTaP can be given in conjunction with other vaccinations. 

DTaP is safe for children under the age of seven. Tdap, which has a lower dosage of diphtheria and pertussis vaccinations, is licensed for adolescents as young as 11 years old and adults as young as 19 years old.

It is sometimes referred to as a booster dose since it improves immunity that has waned as a result of immunizations administered between the ages of 4 and 6. 

References 

  1. https://www.sciencedirect.com/science/article/pii/S0264410X1930893X 
  2. https://www.sciencedirect.com/science/article/pii/S0264410X20304588 
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