Difference Between Glucose and Dextrose

Glucose and dextrose are nearly identical. “Glucose” and “Dextrose” are terms that are frequently utilized similarly.

Dextrose, also called Dextrose Monohydrate or D-Glucose, is the highest prevalent form of glucose. Dextrose is a kind of glucose that occurs spontaneously in foods such as maize, fruits, as well as nectar.

The most prevalent kind of basic sugar present in live things is glucose.

Glucose vs Dextrose

The main difference between glucose and dextrose is that enantiomers of glucose are available, but enantiomers of dextrose do not exist. Glucose and dextrose are two of the most commonly misunderstood words. Much nutritional information uses the words glucose or dextrose. When it comes to brand labeling, some corporations prefer to use the word dextrose instead of glucose since they think the second has a bad meaning.

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Glucose is the most common form of sugar found in the bloodstream and the primary supply of power for the body’s tissues.

Glucose is derived from the meals we consume or can be synthesized by the system from other chemicals. The circulation transports glucose to the tissues.

Numerous hormones, particularly insulin, regulate bloodstream glucose concentrations.

Dextrose is a basic sugar derived from corn or grain that is structurally equivalent to glucose, or bloodstream glucose.

Dextrose is a stimulant that is frequently employed in baked goods and can also be found in packaged foods as well as in corn syrup. Dextrose is also used in medicine.

Comparison Table Between Glucose and Dextrose

Parameters of ComparisonGlucoseDextrose
DefinitionGlucose, having the molecular structure C6H12O6, is a basic sugar.Dextrose is another term for D-glucose.
TypesD-glucose and L-glucose are two types of glucose.Dextrose is exclusively available in the type of D-glucose.
OccurrenceGlucose may be derived from a variety of carbs.Dextrose is mostly derived from carbohydrates.
AbundanceD-glucose is plentiful in the environment, whereas L-glucose is less so.Dextrose is found in abundance in the environment.
EnantiomersEnantiomers of glucose exist.There are no enantiomers of dextrose.

What is Glucose?

Glucose is essential for maintaining the body’s processes in good operating conditions. When our blood sugars are ideal, it is common for us to let them go undetected.

When they deviate from the acceptable bounds, you’ll observe an unfavorable impact on regular performance. It is a monosaccharide since it is the easiest of the sugars. This signifies it just has single sugar. 

Together with fats, glucose is among the body’s primary carbohydrate energy supplies. Glucose is obtained through loaves of bread, fruits, veggies, and milk products.

Food is required to provide the power that allows you to survive. While glucose is essential, like with so many other things, it is best consumed in proportion. 

Abnormal or out-of-control glucose concentrations can have long-term and dangerous consequences. When we ingest, our bodies instantly begin processing glucose.

Enzymes begin the degradation step with assistance from the pancreas. The pancreas, which generates chemicals such as insulin, is essential for how our bodies cope with glucose. 

When we consume, our bodies send a signal to the pancreas that it wants to produce insulin to cope with the growing blood glucose levels.

When your blood glucose levels get too excessive, insulin will assist to lower them. Too-high blood glucose levels are a warning indication for diabetics that they may need to use artificial insulin.

Regular exercise helps reduce your symptoms in less critical instances.

What is Dextrose?

Dextrose is a type of sugar that is derived from starch. Starch is complicated glucose present in many crops, notably corn, wheat, rice, and potatoes.

Corn starch is the greatest prevalent supplier of dextrose. When used as a medicine, dextrose is administered either through the mouth (orally) or via needle. 

Dextrose is sometimes spelled D-glucose. Dextrose is used to cure extremely low blood glucose (hypoglycemia), which is most commonly seen in persons with diabetes mellitus.

Dextrose is injected into the body to cure insulin shock. Dextrose acts by rapidly boosting the level of glucose in the bloodstream.

Glucose may be found in carbohydrate-rich meals such as pieces of bread, porridge, tubers, fruit, spaghetti, and rice. 

Glucose is a fuel resource, and all of your body’s natural tissues and systems require it to operate correctly.

Dextrose can also be used to deliver carb nutrients to someone unable to eat due to sickness, injury, or another health problem.

It is occasionally provided to those who have become ill as a result of excessive alcohol use. 

Hyperkalemia can also be treated with dextrose. The hazards of consuming dextrose are the same as those of consuming any sugar.

Excess dextrose intake can have several short- and long-term consequences. While your body requires some sugar for fuel, ingesting too much might put you at risk for several diseases.

Main Differences Between Glucose and Dextrose

  1. Dextrose is a word that is often used in various pharmacopeias, clinics, and other food goods, whereas glucose is utilized in just a few medicinal commodities.
  2. Glucose is frequently associated with an unfavorable connotation in packaged foods labeling when contrasted to dextrose as it does not have bad connotations.
  3. There are enantiomers of glucose existing, but no enantiomers of dextrose exist in the environment. 
  4. Glucose is not found in abundance, in reality, however, dextrose is found in abundance in reality. 
  5. The two types of glucose are D-glucose and L-glucose whereas dextrose is referred to by another term, which is D-glucose. 


In the world of pharmaceuticals, they frequently employ the opposite ‘” glucose rather than dextrose ‘” solely to avoid misunderstanding.

Furthermore, many health professionals are now using glucose instead of dextrose for the same reason, intending to eventually use the word ‘glucose’ as the popular word for glucose instead of ‘dextrose,’ which further adds to the confusion.

As a result, the choice for either word is solely for promotional purposes. The precise use of both phrases may make or break a product’s brand awareness.

Perhaps many individuals assume that glucose is related to consuming too much calorie intake, causing one to grow fat or overweight.

As a customer, you should be informed that the term “dextrose” on packaged food implies “glucose.”


  1. https://www.ncbi.nlm.nih.gov/pmc/articles/pmc1687736/
  2. https://diabetes.diabetesjournals.org/content/26/12/1178.short
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