Difference Between Azithromycin and Amoxicillin (With Table)

People get bacterial and urinary tract infections. These are not any common infections. Human beings should not ignore them and consider the doctor right away when they have these problems. Two common tablets are used in treating them are Azithromycin, and the other one is Amoxicillin. They are recommended by doctors for treating bacterial infections. 

Azithromycin vs Amoxicillin

The difference between Azithromycin and Amoxicillin is that Azithromycin is used for infections in the lungs, throat, and sinus problems. Amoxicillin is used for treating bacterial infections and urinary tract infections. The treatment days required for Azithromycin are 5 days. On the other hand, the treatment days required for Amoxicillin are 10 days. 

Azithromycin is a medicine that helps people in treating bacterial infections in their bodies. They will kill the growing bacteria in the human body. Over the last few years, it has been widely helpful in treating people with bacterial infections and is still considered scrutiny. If you have a sore throat, then you can take this medicine. It is mostly involved in dealing with infections in the throat, nose, and lungs. 

Amoxicillin is a medicine given for people with bacterial infections. It is one of the fast-reacting medicines. Even though it starts to work faster but finding improvements in your body will take more time. One of the most common side effects that you will experience after taking amoxicillin is vomit. Most people’s bodies will react to this when they take amoxicillin. That is why it is considered to be one of the common side effects. 

Comparison Table Between Azithromycin and Amoxicillin

Parameters of ComparisonAzithromycinAmoxicillin
Brand nameZithromaxTrimox and Amoxil
Typical Treatment Days5 days but it also varies depending upon the severity7-10 days but it also varies depending upon the severity
Drug formTablets, injection, and eye dropsCapsule and tablet
Class Macrolide antibioticPenicillin antibiotic
Dosage Per Day2 tablets500 mg

What is Azithromycin?

It is an antibiotic that is used for treating chest infections. It is for curing nose, skin infections, sinus infections, and also some sexually transmitted infections as well. It will stop the growth of bacteria inside the human body. Once a human body gets infected, bacteria will start to grow inside that. To stop that, we need some powerful medicine. That is where Azithromycin comes to our help.

Remember that it will work for any common infections like cold and flu. In simple words, we can’t use this medicine to treat viral infections. It is meant only for curing bacterial infections. It is given for 3 days to the affected person. Even though they are giving it only for 3 days, the effect will be like 10 days and will help in curing the infection faster. It is also used for curing acute respiratory tract infections as well. Once you take azithromycin, it will take seven days to start working in your body.

People who have a low amount of magnesium in their bodies should not take this medicine. It will worsen their condition further. Also, people having low potassium in their bodies and having skeletal disease should avoid consuming this. Once you take this medicine, it will be in your body for 15.5 days and will protect you from bacterial infections in those 15 days. If you have a frequent cough, then you can take azithromycin for that. But again, you have to consult a doctor first without taking medicines. 

What is Amoxicillin?

It is used for treating bacterial infections, mostly in the areas of the chest and also urinary tract infections. Doctors often give this to children when they have ear and chest infections. These types of infections are common in children. The best and fast way to cure them is by giving this medicine to them. This is one of the string antibiotics which helps in killing the growth of bacteria inside the human body. 

IF you get any allergy after intaking this medicine, like developing skin rashes, feeling shortness in breathing, find any swelling in your body, and trouble in breathing, then you have to call the doctor immediately. Because the condition will then develop into serious problems if you ignore them. In some severe cases, it can cause diarrhoea as well. When taking amoxicillin, you should stop avoid eating some other foods as well.

The foods that should be avoided during the intake of amoxicillin are grapefruit, alcohol, and foods that have excess calcium. These will worsen your condition further. Because these foods don’t go well with amoxicillin. When you take an amoxicillin tablet, it will start working within one or 2 hours. It will start to react in the human body very faster than your anticipation. 

Main Differences Between Azithromycin and Amoxicillin

  1. The brand name of Azithromycin is Zithromax. On the other hand, the brand name of Amoxicillin is Trimox and Amoxil.
  2. The days required for the treatment of Azithromycin is 5 days, and it can vary as well. But the days required for the treatment of Amoxicillin are 10 days, and it can vary as well.
  3. The drug form is available in tablet, injection, and eye drops. On the other hand, the drug form is available in tablets and capsules.
  4. Azithromycin’s class of drug is macrolide antibiotic. Amoxicillin’s class of drug is penicillin antibiotic.
  5. The string dosage recommended by the doctor per day for azithromycin is 2 tablets. For amoxicillin is 500 mg per day.


Both these are used by people for treating bacterial and urinary tract infections. When we have any bacterial and sinus infections, we should not ignore or hesitate to meet a doctor. Because it could lead to some other complicated problems as well. People who are taking these medicines should also see if they have any allergies to the medicine or not.

Because some people’s bodies might react suddenly to the medicine and some others don’t. If your body gets allergic to it, then you should immediately consult the doctor. In some severe cases, there will be more complications that will be difficult to treat. So, the faster we sense some discrepancies, we should react to them immediately.


  1. https://www.scielo.br/j/jbpneu/a/8pNgSy5FVg3mTBWw84cKYnR/?format=pdf&lang=en
  2. https://www.hindawi.com/journals/idog/2001/873741/
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