Difference Between Azithromycin and Erythromycin

Azithromycin and erythromycin are macrolide drugs used to treat soft tissue infections, upper and lower respiratory tract infections, and urinary tract and vaginal infections.


Science Quiz

Test your knowledge about topics related to science

1 / 10

A chemical reaction where energy is released is called:

2 / 10

Which of the gas is not known as green house gas?

3 / 10

Non-stick cooking utensils are coated with

4 / 10

Fermentation is the process of ______.

5 / 10

The element common to all acids is

6 / 10

Name the metal which is easily cut by a simple knife?

7 / 10

Which of the following compound is mainly used in hand sanitizer?

8 / 10

A bond that occurs between nonmetals and nonmetals is called a/an _________.

9 / 10

What is the other name of Newton's first law of motion?

10 / 10

Potassium Permanganate is used for purifying drinking water, because

Your score is


Azithromycin is a derivative of erythromycin. However, they are different in terms of mechanism and onset of action. There are several variables that may affect the drugs recommended by the doctor.

Azithromycin vs Erythromycin

The difference between Azithromycin and Erythromycin is that the Azithromycin has a considerable half-life in the end. This might be due to the drug’s extremely wide absorption and release from the tissues.

Erythromycin is processed mostly in the liver of humans. It’s mostly excreted in the bile, though some of it also ends up in the urine. The half-life of erythromycin is roughly 1.5 hours.

Both of these antibiotics have the potential to interfere with the effectiveness of birth control tablets.

Azithromycin vs Erythromycin

Want to save this article for later? Click the heart in the bottom right corner to save to your own articles box!

Azithromycin is a drug that aids in the treatment of bacterial infections in the body. They will eliminate the germs that are developing in the human body.

In recent years, it has been proven to be generally beneficial for the treatment of bacterial infections and is currently undergoing examination.

If you have a sore throat, you can take this medicine. It is mostly used to treat infections of the throat, nose, and lungs.

Erythromycin is primarily used to treat infections caused by penicillin resistance. It offers more protection against infections of the upper respiratory tract.

Your doctor may prescribe erythromycin in the form of pills, slow-release capsules, ophthalmic solutions and ointments, gels, and other forms. Erythromycin’s specific method of action is unknown.

It is known, however, that it may have bactericidal properties. Azithromycin works by preventing germs from growing in the body. This is accomplished by interfering with their protein production.

Comparison Table

Parameters of Comparison AzithromycinErythromycin
DescriptionZithromax (azithromycin) is a generic antibiotic that can be used to treat a variety of bacterial illnesses. It may, however, induce headaches, dizziness, or a rash.Ery-Tab (Erythromycin) is an antibiotic that may be used to treat a range of bacterial infections. Before using it, check for medication interactions.
TreatsTreats bacterial infections.Prevents and treats infections.
Half Life53 hours2 hours
Side effectsHighLow
Dosage formIntravenous powder for injection
Oral powder
Oral tablet
Oral capsule
Oral tablet
Oral suspension

What is Azithromycin?

Azithromycin is a kind of antibiotic. It’s commonly used to treat chest infections like pneumonia, and throat infections and some sexually transmitted diseases.

Azithromycin is commonly used to treat ear infections and chest infections in children. It can also be administered for a long time to avoid chest infections in patients who are frequently infected.

The medication is available as capsules, pills, and a drinkable liquid on prescription. It can also be given by injection, but this is usually done in a hospital setting.

Zithromax is another brand name for Azithromycin. Azithromycin is generally considered to be safe to use. However, nausea, vomiting, stomach discomfort, or diarrhoea are all possible adverse effects.

Long-term usage of the medicine may result in increased bacterial resistance in isolates, as well as hearing loss. It has the potential to produce allergic responses, albeit these are uncommon.

As a result, Azithromycin is only available to people on prescription. It’s also used to treat pneumonia and diarrhoea caused by travel. Many doctors use it in combination with other malaria medications. It can be taken orally or injected directly into the veins.


What is Erythromycin?

Erythromycin is an antibiotic that is used to treat a wide range of bacterial illnesses. It may also be used to inhibit the spread of germs.

The antibiotic erythromycin belongs to the macrolide family of antibiotics. It works by preventing germs from growing. Only bacterial illnesses are treated or prevented with this antibiotic. It is ineffective against viral infections.

When an antibiotic is used when it isn’t needed, it loses its effectiveness for future illnesses. Adults, including pregnant and nursing mothers, can take erythromycin.

Children are able to take erythromycin. Certain persons should not take erythromycin. Nausea, vomiting, and stomach discomfort are all possible side effects of erythromycin.

As a result, the doctor may not recommend them as a first-line treatment, particularly Erythromycin. These drugs may cause adverse responses in patients, such as urticaria and anaphylaxis.

Erythromycin is also used to prevent heart infections in persons who are having dentistry or other operations done.


Main Differences Between Azithromycin and Erythromycin

  1. Zithromax (Azithromycin) is a generic antibiotic that can be used to treat a variety of bacterial illnesses. It may, however, induce headaches, dizziness, or a rash, whereas Ery-Tab (Erythromycin) is an antibiotic that may be used to treat a range of bacterial infections. Before using it, check for medication interactions.
  2. Azithromycin treats bacterial infections, whereas Erythromycin prevents and treats infections.
  3. Azithromycin half-life is of 53 hours, whereas Erythromycin half-life is of 2 hours.
  4. Azithromycin has a high frequency of side effects than Erythromycin, whereas Erythromycin has less frequency of side effects.
  5. The azithromycin dosage form is Intravenous powder for injection, oral powder for reconstitution, Oral tablet, whereas Erythromycin dosage form is an Oral capsule, Oral tablet, Oral suspension
Difference Between Azithromycin and Erythromycin
  1. https://www.sciencedirect.com/science/article/pii/S0029784497005863
  2. https://europepmc.org/article/med/8008325
One request?

I’ve put so much effort writing this blog post to provide value to you. It’ll be very helpful for me, if you consider sharing it on social media or with your friends/family. SHARING IS ♥️

Leave a Comment

Your email address will not be published. Required fields are marked *