Difference Between Oxycontin and Oxycodone (With Table)

Oxycontin And Oxycodone are both medications that are used as pain killers. Both the medications have characteristics to produce a morphine-like effect to reduce the pain in your body. These medicines can have side effects, so they should always be taken when recommended by a doctor.

Oxycontin vs Oxycodone

The main difference between Oxycontin and Oxycodone is that Oxycontin is an extended-release form, an extended version of oxycodone. Oxycontin is another brand name for oxycodone with higher concentrations of oxycodone present in it.There is not much difference between the two medications. They are both pain relief medication.

Oxycontin is a very strong pain killer which is used to help to get relief with severe ongoing pain. They are given to cancer patients to liberate their pain. These are not occasional medications that can be used for moderate pain. These are prescribed tablets, their overdose can highly affect your health.

Oxycodone is a pain killer which is sold under the brand name Roxicodone and oxycontin. It is an opioid medication and is a highly addictive drug which is why it should be taken when advised by a doctor. This medicine provides relief in 15 minutes which can last up to six hours. It is available in combinations with other medicines as well.

Comparison Table Between Oxycontin And Oxycodone

Parameters of ComparisonOxycontinOxycodone
What are they? A pain killer drug is used to treat patients who have severe pain like cancer patients.It is a pain killer which is an opioid medication.
Side effectsNausea, vomiting, constipation, weakness, headache, Respiratory issues, low blood pressure, Itching, Rashes, etc.  Addiction, hallucinations, nausea, vomiting, sweating heavily, dizziness, loss of appetite, low blood pressure, etc.
BioavailabilityIt is mostly taken as a tablet with oral bioavailability of 60 to 87%.It can be taken as a tablet by mouth or by injection.
Onset of actionStarts providing relief 10 to 30 minutes and can last up to 3 to 6 hours for immediate release formulation. For controlled-release formulations, it starts providing relief within 1 hr which lasts up to 12 hours.It provides relief within fifteen minutes and lasts for up to six hours.
Excretion8% to 14% is excreted over 24 hours.83% of it is excreted through urine.

What is Oxycontin?

Oxycontin is a pain killer, a controlled drug which is used in cases with patients who have severe ongoing pain like cancer patients. This medication is an extended version of Oxycodone. It contains higher concentrations of oxycodone. The medication has to be taken under guidance. Regular use without a prescription can lead to addiction as it is a narcotic drug. It gives a feeling of relaxation and euphoria as the medicine starts to work. The medicine starts its effect within 10 to 30 minutes to provide relief.

It has side effects like Nausea, vomiting, sweating, dry mouth, constipation, weakness, headache, Respiratory issues, low blood pressure, Itching, Rashes, difficulty in swallowing, loss of apatite, change in blood pressure, etc.

The long-term use of this medication will also cause fatal effects like it can cause opiate use disorder, memory loss, kidney or liver failure, severe tolerance, and can cause problems solving skills, etc. The overdose of the medicine is fatal as it can lead to nausea, cardiovascular hyperactivity, Extreme lethargy state, urine retention, kidney or liver failure, etc. The abrupt withdrawal of the medicine can also be harmful, it can lead to anxieties and thoughts of suicide.

What is Oxycodone?

Oxycodone is a generic medication that is used as a pain killer. It is an opioid medication which means it is an opiate agonist. It initiates a physiological response when combined with a receptor called endogenous opioid receptors. They activate the neurotransmitters which eventually results in relief from pain.

Oxycodone is a highly addictive drug so it should only be taken by a doctor’s prescription. It can cause side effects like addiction, hallucinations, nausea, vomiting, sweating heavily, dizziness, loss of appetite, low blood pressure, shallow breathing, etc. The Overdose of oxycodone can lead to slow heart rate, cold skin, respiratory arrest, spinal cord infarction, low blood pressure, breathing problems, and even death.

The medication is available in combinations with various tablets like paracetamol, Ibuprofen, aspirin, etc. The medication is available in a variety of formulation mainly in immediate release and controlled release formulations.

This medication can be taken in the form of tablets as well as injections. It provides relief in 15 to 20 minutes. If you are taking this medicine don’t take it frequently neither withdraw it abruptly. Withdrawing the medicine can lead to severe effects as well. Check with your doctor before taking any step.

Main Differences Between Oxycontin And Oxycodone

  1. Oxycontin is a narcotic pain killer drug medication with higher concentrations of oxycodone.
  2. Oxycontin takes up to 10 to 30 minutes to provide relief and can last up to 3 to 6 hours for immediate release formulation. For controlled-release formulations, it starts providing relief within 1 hour which lasts up to 12 hours. oxycodone provides relief within fifteen minutes and lasts for up to six hours.
  3. Oxycontin as prescribed by doctors has to be taken only after 12 hours. Oxycodone can be taken after 4.5 hours.
  4. Oxycontin is excreted almost 8% to 14% over 24 hours. 83% of Oxycodone is excreted through urine.
  5. Both the drugs are highly effective. The overdose of any of them can be fatal. Oxycontin is more deadly as it contains higher concentrations of oxycodone.

Conclusion

Oxycontin and Oxycodone are both pain killers which are used for severe pain. Oxycontin is an extended version of oxycodone. Both the medications are highly addictive, their overdose can cause serious health problems. Their overdose can even lead to death.

Both the medications have to be strictly taken under the doctor’s guidance. Usually, they are taken every 12 hours. The dosage is based on the medical condition of the patient and response to treatment. These medications have severe side effects. If they have been used with wrong drugs and are not used as prescribed they can be fatal.

References

  1. https://headachejournal.onlinelibrary.wiley.com/doi/abs/10.1111/j.1526-4610.2004.04008.x
  2. https://www.nejm.org/doi/full/10.1056/NEjMc1204141
  3. https://www.sciencedirect.com/science/article/pii/S0885392405000369
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