Difference Between Frontline and Frontline Plus

Frontline is a product that helps in the maintenance of animal hygiene. The product contained fipronil and was launched in 1997. Frontline's main objective is to remove the fleas and ticks present on the body of the pet.

Frontline Plus is a hygiene product that helps in the maintenance of ticks and fleas on the pet's body. It contains fipronil and methoprene and is applied topically (applying the product directly to the skin surface).

Comparison Table Between Frontline and Frontline Plus

Parameters of ComparisonFrontlineFrontline Plus
DescriptionMedication is used for pets to remove insects from the pet’s body.Medication is used for pets to remove insects from the pet’s body mainly in cats and dogs.
Released in19972000
ManufacturerMerialMerial
Active ingredientFipronilFipronil and methoprene
MechanismFipronil attacks the nervous system of the parasites, which results in the death of ticks and fleas.Fipronil attacks the nervous system of the parasites, which results in the death of ticks and fleas. S-methoprene disrupts the life cycle of the parasites rendering its growth.
Duration of actionActs after 24 hours of topical administration and offer protection up to 30 days.Acts after 24 hours of topical administration and offer protection up to 30 days.
Ideal forIndoor petsOutdoor pets
Side effectsCan cause irritation or itching after application. It should not be used on dogs who are alcohol-sensitive or sensitive to insecticides.It should not be used on dogs who are alcohol-sensitive or sensitive to insecticides.

 What is Frontline?

Frontline is an animal hygiene product that was launched in 1997. It aims to remove the fleas and ticks present on the body of the pet. It is effective against all the grown ticks and fleas.

The active ingredient present in Frontline is fipronil. Fipronil is a broad-spectrum phenylpyrazole insecticide classified as WHO class II and is moderately hazardous.

The disadvantage of frontline is that it is effective only against grown fleas and ticks. It cannot kill the larvae or the eggs of the insects. This is mostly used for pets who stay indoors owing to the disadvantage of the medicine.

What is Frontline Plus?

Frontline Plus is a healthcare product that was launched in 2000 and is used to control the ticks and fleas on the body of pets. It is more like an upgraded version of Frontline having more than one active medicine in it.

The main active medicine in this is fipronil along with methoprene. Fipronil is a broad-spectrum phenylpyrazole insecticide classified as WHO class II and is moderately hazardous.

Frontline plus interrupts the flea's life cycle and prevents their maturity. This gives the medication an advantage of control over all of the tick and flea population. This is more suitable for pets who stay outdoor more.

Main Differences Between Frontline and Frontline Plus

  1. Frontline is more suitable for indoor pets, while frontline plus is preferred for outdoor pets.
  2. Frontline offers partial protection against ticks and fleas while frontline plus offers full-fledged protection against all of the tick and flea population.

Conclusion

While there are abundant products available in the market, one of the major manufacturers is Merial which is engaged in the product of two of the widely known products: Frontline and Frontline plus.

Frontline is a topically applied product having fipronil and is used to eliminate the ticks and fleas on the skin of the pet. Frontline plus is also topically applied and has two of the components, namely fipronil and methoprene.

References

  1. https://www.researchgate.net/profile/Michel-Franc/publication/5665984_Efficacy_of_fipronil-S-methoprene_on_fleas_flea_egg_collection_and_flea_egg_development_following_transplantation_of_gravid_fleas_onto_treated_cats/links/54b242320cf28ebe92e19505/Efficacy-of-fipronil-S-methoprene-on-fleas-flea-egg-collection-and-flea-egg-development-following-transplantation-of-gravid-fleas-onto-treated-cats.pdf
  2. https://krex.k-state.edu/dspace/handle/2097/14772
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