Frontline vs Frontline Plus: Difference and Comparison

There is an abundant number of healthcare management and hygiene management product available for both humans and animals. As people love animals, especially their pets, a wide variety of hygiene maintenance and health supplement products are available for them.

Key Takeaways

  1. Frontline and Frontline Plus are flea and tick control products for pets, but Frontline Plus has an additional ingredient to kill flea eggs and larvae.
  2. Frontline is a topical treatment that kills fleas and ticks for up to one month, while Frontline Plus protects for up to three months.
  3. Frontline Plus is recommended for pets frequently exposed to flea and tick infestations, while Frontline is suitable for pets with occasional exposure to these parasites.

Frontline vs Frontline Plus

Frontline offers partial protection against insects such as fleas and ticks, while the latter offers complete protection against insects and their larvae. These two products are meant to ensure hygiene for pets like cats and dogs. They can be used without any prescription from a veterinary doctor. The products are applied topically, effective after twenty-four hours of application, and provide protection for up to thirty days.

Frontline vs Frontline Plus
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Frontline is a product that helps in the maintenance of animal hygiene. The product contained fipronil and was launched in 1997. Frontline’s main objective is to remove the fleas and ticks present on the body of the pet.

Frontline Plus is a hygiene product that helps maintain ticks and fleas on the pet’s body. It contains fipronil and methoprene and is applied topically (applying the product directly to the skin surface).

Comparison Table

Parameters of ComparisonFrontlineFrontline Plus
DescriptionMedication is used for pets to remove insects from the pet’s bodies.Medication is used for pets to remove insects from the pet’s body, mainly in cats and dogs.
Released in19972000
ManufacturerMerialMerial
Active ingredientFipronilFipronil and methoprene
MechanismFipronil attacks the nervous system of the parasites, which results in the death of ticks and fleas.Fipronil attacks the nervous system of the parasites, which results in the death of ticks and fleas. S-methoprene disrupts the life cycle of the parasites rendering its growth.
Duration of actionIt acts after 24 hours of topical administration and offers protection for up to 30 days.It acts after 24 hours of topical administration and offers protection for up to 30 days.
Ideal forIndoor petsOutdoor pets
Side effectsIt can cause irritation or itching after application. It should not be used on alcohol-sensitive dogs or insecticide-sensitive dogs.It should not be used on alcohol-sensitive dogs or insecticide-sensitive dogs.

 What is Frontline?

Frontline is an animal hygiene product that was launched in 1997. It aims to remove the fleas and ticks present on the body of the pet. It is effective against all the grown ticks and fleas.

The active ingredient present in Frontline is fipronil. Fipronil is a broad-spectrum phenylpyrazole insecticide classified as WHO class II and is moderately hazardous.

The disadvantage of the frontline is that it is effective only against grown fleas and ticks. It cannot kill the larvae or the eggs of the insects. This is mainly used for pets who stay indoors owing to the disadvantage of the medicine.

frontline

What is Frontline Plus?

Frontline Plus is a healthcare product launched in 2000 and used to control the ticks and fleas on the body of pets. It is more like an upgraded version of Frontline, with more than one functional medicine.

The primary active medicine in this is fipronil, along with methoprene. Fipronil is a broad-spectrum phenylpyrazole insecticide classified as WHO class II and is moderately hazardous.

Frontline plus interrupts the flea’s life cycle and prevents its maturity. This gives the medication the advantage of control over the tick and flea populations. This is more suitable for pets who stay outdoors.

frontline plus

Main Differences Between Frontline and Frontline Plus

  1. Frontline is more suitable for indoor pets, while frontline plus is preferred for outdoor pets.
  2. Frontline offers partial protection against ticks and fleas, while frontline plus offers full-fledged protection against all tick and flea populations.
References
  1. https://www.researchgate.net/profile/Michel-Franc/publication/5665984_Efficacy_of_fipronil-S-methoprene_on_fleas_flea_egg_collection_and_flea_egg_development_following_transplantation_of_gravid_fleas_onto_treated_cats/links/54b242320cf28ebe92e19505/Efficacy-of-fipronil-S-methoprene-on-fleas-flea-egg-collection-and-flea-egg-development-following-transplantation-of-gravid-fleas-onto-treated-cats.pdf
  2. https://krex.k-state.edu/dspace/handle/2097/14772

Last Updated : 13 July, 2023

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